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Parcourir par auteur "Trikalinos, T. A."

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    • Extreme between-study homogeneity in meta-analyses could offer useful insights 

      Ioannidis, J. P. A.; Trikalinos, T. A.; Zintzaras, E. (2006)
      Objectives: Meta-analyses are routinely evaluated for the presence of large between-study heterogeneity. We examined whether it is also important to probe whether there is extreme between-study homogeneity. Study Design: ...

    • A heterogeneity-based genome search meta-analysis for autism-spectrum disorders 

      Trikalinos, T. A.; Karvouni, A.; Zintzaras, E.; Ylisaukko-oja, T.; Peltonen, L.; Jarvela, I.; Ioannidis, J. P. A. (2006)
      Autism and autism-spectrum disorders exhibit high heritability, although specific susceptibility genes still remain largely elusive. We performed a heterogeneity-based genome search meta-analysis (HEGESMA) of nine genome ...

    • Lack of replication of thirteen single-nucleotide polymorphisms implicated in Parkinson's disease: a large-scale international study 

      Elbaz, A.; Nelson, L. M.; Payami, H.; Ioannidis, J. P.; Fiske, B. K.; Annesi, G.; Carmine Belin, A.; Factor, S. A.; Ferrarese, C.; Hadjigeorgiou, G. M.; Higgins, D. S.; Kawakami, H.; Krüger, R.; Marder, K. S.; Mayeux, R. P.; Mellick, G. D.; Nutt, J. G.; Ritz, B.; Samii, A.; Tanner, C. M.; Van Broeckhoven, C.; Van Den Eeden, S. K.; Wirdefeldt, K.; Zabetian, C. P.; Dehem, M.; Montimurro, J. S.; Southwick, A.; Myers, R. M.; Trikalinos, T. A. (2006)
      Background: A genome-wide association study identified 13 single-nucleotide polymorphisms (SNPs) significantly associated with Parkinson's disease. Small-scale replication studies were largely non-confirmatory, but a ...

    • Meta-Analysis Methods 

      Trikalinos, T. A.; Salanti, G.; Zintzaras, E.; Ioannidis, J. P. A. (2008)
      Meta-analysis is the quantitative synthesis of information from several studies. It is applicable to a variety of study designs in genetics, from family-based linkage studies and population-based association studies to ...